Commonly used intracellular immunohistochemical stains
| Stain | Normal cells stained |
|---|---|
| Cytokeratin* | Epithelial cells |
| Desmin* | Muscle cells |
| GFAP* | [[Glial cells |
| Neurofilament* | Neurons |
| Vimentin* | Mesenchymal cells (eg, fibroblasts) |
| Chromogranin | Neuroendocrine cells |
| Synaptophysin | Neurons |
| S100 | Neural crest-derived cells (eg, melanocytes) |
*Intermediate filaments (cytoskeletal structural components).
Intermediate filaments
- Functions: maintain cell structure
- Examples: cytokeratin (in epithelial cells), vimentin (in fibroblasts), desmin (in muscle fibers), glial fibrillary acid proteins (GFAP, in glial cells), neurofilaments (in nerve cells), nestin (in neuronal stem cells), lamins (in cell nucleus)