Epidemiology


Endemic in western US (as scattered cases in rural areas)

Etiology


  • Pathogen: Yersinia pestis
  • Reservoir: prairie dogs, squirrels, rodents
  • Transmission
    • Bites by infected fleas

Pathophysiology


Clinical features


  • Bubonic plague (most common)
    • Sudden onset of fever, headache, myalgias, chills, and painful swollen lymph nodes (buboes)
    • May progress to sepsis, pneumonia, and meningitis.
  • Pneumonic plague
    • Signs of pneumonia
    • Rapid progression with possible respiratory failure and shock
  • Septicemic plague: clinical features of sepsis, possible shock, abdominal pain

Diagnostics


Treatment