Causes of tender hepatomegaly
Acute hepatitis
Impaired venous outflow
- Budd-Chiari syndrome
- Right heart failure
- Hepatic sinusoidal obstruction syndrome (SOS)
- Peliosis hepatis
Causes of nontender hepatomegaly
Cholestatic liver disease
Storage disorders
Infiltrative diseases
- Granulomatous disease
- infection (eg, tuberculosis)
- autoimmune conditions (eg, sarcoidosis)
- drug-induced liver injury
- Hepatic amyloidosis
- Hepatosplenic T cell lymphoma
- Malignant tumors
- hepatocellular carcinoma
- cholangiocarcinoma
- Benign lesions