| Condition | HCG | PAPP-A | Nuchal translucency |
|---|---|---|---|
| Trisomy 21 | ↑ | ↓ | ↑ |
| Trisomy 18 | ↓ | ↓ | ↑↑ |
| Trisomy 13 | ↓ | ↓ | ↑ |
Down syndrome
Edwards syndrome
Rocker-bottom feet can also be found in Patau syndrome.
Patau syndrome
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| Condition | HCG | PAPP-A | Nuchal translucency |
|---|---|---|---|
| Trisomy 21 | ↑ | ↓ | ↑ |
| Trisomy 18 | ↓ | ↓ | ↑↑ |
| Trisomy 13 | ↓ | ↓ | ↑ |
Rocker-bottom feet can also be found in Patau syndrome.