• Classification: based on radiological findings
• Osteoblastic metastasis
  • New bone formation by osteoblasts outweighs osteolytic processes → increase in radiographic density
  • Examples: prostate cancer, small cell lung cancer
• Osteolytic metastasis
  • Osteolytic processes outweigh new bone formation → decrease in radiographic density
  • Examples: multiple myeloma, thyroid cancer, kidney cancer, melanoma, non-small cell lung cancer
• Mixed metastasis: e.g., breast cancer, gastrointestinal cancer