• Platelet disorder
  • Small and superficial
  • Mucocutaneous bleed with minor trauma, small ecchymoses or petechiae
• Coagulation factors disorder
  • Large and deep
  • Large hematomas, muscle bleed or hemarthrosis

---

• Increased PT
  • Factor VII deficiency
  • Monitoring of vitamin K antagonist therapy (INR)
• Increased aPTT
  • Hemophilia
  • Severe cases of von Willebrand disease
  • SLE (if lupus anticoagulant is present)
  • Monitoring of unfractionated heparin (UFH) therapy
• Increased PT and aPTT
  • Vitamin K deficiency
  • DIC