Etiology
- Bone marrow aplasia
- Aplastic anemia
- Infection (eg, parvovirus, HIV, viral hepatitis)
- Nutritional deficiency (eg, vitamin B12/folate)
- Medications (eg, hydroxyurea)
- Bone marrow infiltration
- Cancer (eg, hematologic, metastatic)
- Myelofibrosis
- Infection (eg, tuberculosis, fungal infection)
- Mature blood cell destruction
- Intravascular (eg, DIC, TTP)
- Extravascular (eg, hypersplenism)