Large-vessel vasculitis
See Takayasu arteritis
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Medium-vessel vasculitis
See Polyarteritis nodosa
Also add Thromboangiitis obliterans
Clinical features
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- Migratory superficial thrombophlebitis (recurrent): often seen prior to the onset of limb ischemia
- Tender nodules along the course of the affected vein
- Raynaud phenomenon
- Chronic or acute limb ischemia: may progress from distal to proximal vessels
- Intermittent claudication
- Pain at rest, cool extremities, and/or diminished or absent pulses
- Ulceration and/or gangrene of fingertips and/or toes (digits may autoamputate)
Small-vessel vasculitis
ANCA-associated small-vessel vasculitis
See Granulomatosis with polyangiitis
Granulomatosis with polyangiitis (Wegener granulomatosis)
Microscopic polyangiitis
Non-ANCA-associated small-vessel vasculitis
IgA vasculitis, also known as Henoch-Schönlein purpura