(formerly known as Clara cells)

• Maintain the integrity of the respiratory epithelium by secreting specialized immunomodulatory proteins, glycoproteins, and lipids.
• Cytochrome P450-dependent degradation of toxins
• Act as a reserve for ciliated cells to restore bronchiolar epithelium (stem cell properties)
• Nonciliated, secretory, cuboidal cells located in the terminal and the respiratory bronchioles of the lung